The purpose of this study was to determine the effects of oral supplementation of Longvida®

400 mg/day on muscle & ADL soreness, creatine kinase, and inflammatory cytokines following EMID. Subjects were randomly assigned to either curcumin or placebo (rice flour) and supplemented 2 days before to 4 days after EMID. Blood samples were collected prior to, and 1, 2, 3, and 4 days after EIMD to measure CK and inflammatory cytokines. Curcumin supplementation resulted in significantly smaller increases in CK (− 48%), TNF-α (− 25%), and IL-8 (− 21%) following EIMD compared to placebo.

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